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8-step young stroke protocol: dissection, PFO, thrombophilia & prevention.
Young Stroke Pathway is a clinical reference tool for neurologists, stroke physicians, and trainees managing ischaemic stroke in patients under 55. Standard stroke investigations miss the majority of causes in young patients — traditional vascular risk factors explain only ~30% of cases. This app provides a structured 8-step protocol based on ESO Young Stroke guidelines and NICE NG128. What's covered: • Step 1 – Overview & immediate checklist (first 24h actions) • Step 2 – Cervical artery dissection (MRI T1 fat-sat, CADISS trial, antiplatelet vs anticoagulation) • Step 3 – PFO & RoPE Score Calculator (CLOSE, REDUCE, RESPECT trial evidence) • Step 4 – Full investigation screen (thrombophilia, APS, monogenic, drug screen, cardiac workup) • Step 5 – Contraception & pregnancy (OCP contraindications, safe alternatives, puerperium risk) • Step 6 – Secondary prevention (aetiology-specific treatment, work, driving, psychosocial) • Step 7 – Vasculitis, RCVS & rare causes (PACNS, RCVS, CVT, endocarditis) • Step 8 – Follow-up & MDT (young stroke clinic, lifelong review, pre-discharge checklist) Built by a NHS Neurology & Stroke Fellow. References: CADISS, CLOSE, REDUCE, RESPECT, ISCVT, TRAPS, ESO Young Stroke, NICE NG128. For use by qualified healthcare professionals. Not a substitute for clinical judgement.